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Alexa Fleckenstein M.D.

Blog: On Health. On Writing. On Life. On Everything.

Gluten Intolerance On the Rise

September 28, 2010
Tags: food, additives, antibiotics, chewing, digestion, drugs – prescription, drugs - recreational, eating habits, food – adulterated, food coloring, food – “new and improved”, gluten, gluten intolerance, Gluten Intolerance On the Rise. preservatives, probiotics, snacks
Not only is gluten intolerance widely under-diagnosed, it is also getting more common, especially in the elderly. The reason are still puzzling the researcher. I would venture four explanations (there are very likely more!): 1. Increased use of antibiotics. Antibiotics disturb the fragile balance of bacteria in the gut – there fore it is always good to question your doctor’s wisdom to prescribe and antibiotic. And if you really have to take one, also take plenty of probiotics – but not at the same time: Space it so that you take the probiotic in between antibiotic doses. 2. Increased use of adulterated “foods” – stuff your body doesn’t even recognize as food: additives, preservatives, colorings, prescription and recreational drugs (it is totally beyond me why those drugs are called “recreational’!), “new and improved” food items like Olestra, and so on, and so on. 3. Increase use of milk and dairy products that are highly changed through pasteurization, homogenization and addition of modern “food technology.” Mind, I don’t condone unpasteurized milk for reasons of infection. But I just think milk is for cow babies – and should stay with them. 4. Our eating habits: Not chewing well enough, eating late at night, eating snacks all the time. That way, the body is always busy with digesting – never has time for repair. On the other hand, it is never too late to clean up your eating act: Eat fresh, unadulterated foods, cook for yourself and your family – there is no pursuit more worthwhile in life! Read More 
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Gluten-Related Symptoms and Diseases

September 24, 2010
Tags: order, abdominal pain, acanthosis nigricans, Addison’s disease, ADHD, Alcoholism, alkaline phosphatase (bone) elevated, allergic rhinitis, alopecia areata (patchy hair loss), amenorrhea (absence of menstrual period), anemia, anemia – iron deficiency, anemia – refractory, anemia - vitamin B12 deficiency, anti-endomysium antibodies (EMA), anti-gliadin antibodies (AGA), anti-tissue-transglutaminase antibodies (tTG), antiphospholipid syndrome (frequent miscarriages and other problems), anxiety, aortic vasculitis, apathy, aphthous ulcers, appetite – poor, arthritis, arthritis – enteropathic, arthritis - juvenile idiopathic, asthma, ataxia, ataxia - progressive myoclonic, atherosclerosis, Attention Deficit Hyperactive Disorder (ADHD), Autism, learning disorders, autoimmune cholangitis, autoimmune diseases, autoimmune hepatitis, autoimmune thyroid disease, balding – premature, bipolar disorder, Bitot’s spots (foamy patches on whites of eye), bleeding – unexplained, blepharitis, bloating, blurred vision, bone fracture, bone pain, brain atrophy, brain fog, bronchiectasis, cachexia (general wasting), calcium – low, cancer - small cell of the esophagus, cancer (adenocarcinoma) of the small intestine, cancer of the esophagus, cancer of the pharynx, Candida infections – recurrent, cardiomegaly, casein intolerance, cataracts, cerebral perfusion abnormalities, cheilosis (cracked lips and corners of mouth), cholesterol – low, chorea, chronic bullous dermatosis, chronic fatigue syndrome, colitis, common variable immunodeficiency, complications during pregnancy – labor - delivery and post-partum period, congenital anomalies, constipation, copper deficiency, coronary artery disease, cortical calcifying angiomatosis, cow mill “allergy”, cutaneous vasculitis, cutis laxa, cystic fibrosis, dairy intolerance, delusions, Dementia, depression, dermatitis herpetiformis, dermatomyositis, diabetes type I, diabetes type II, diarrhea, disorientation, Down syndrome, dry eyes, duodenal ulcers, dysmenorrhea (painful menstrual periods), dyspareunia (painful sexual intercourse), dysphagia (difficulty swallowing), early menopause, easy bruising, ecchymosis, eczema, edema, Enteropathy Associated T-cell Lymphoma (EATL), epilepsy, erythema nodosum, esophageal motor abnormalities, eyes – dry, eyes – bloodshot, erythema elevatum diutinum, failure to thrive, fatigue, fatty liver, folic acid (folate) deficiency, food allergies - blood-mediated and cell mediated, food cravings, gall bladder – impaired motility, gas, gastric emptying – delayed, gastritis, GERD - Gastro-Esophageal Reflux Disease, glucose abnormalities - too low or too high, gluten, Gluten-Related Symptoms and Diseases, Grave’s Disease, growth retardation, gums – bleeding and swollen, hair loss, hallucination, headache, Heartburn, heart disease, hemochromatosis, hemosiderosis - idiopathic pulmonary, hepatic granulomatous disease, high blood pressure, homocysteine elevated, hyperactivity, hyperkeratosis – follicular, hyperparathyroidism, hypertension, hyperthyroidism, hypocalciuria, hypogonadism, hypoparathyroidism, hyposplenism (atrophy of spleen), Hypothyroidism, hypotonia, ichthyosis – acquired, pulmonary hemosiderosis – idiopathic, IgA deficiency, IgA nephropathy, impotence, inability to concentrate, infertility, insomnia, intrauterine growth retardation, iron deficiency anemia in pregnancy – severe, irritable bowel syndrome, keratoconjunctivitis sicca, keratomalacia, kidney stones, lactose intolerance, lassitude, late menarche (late start of menstrual periods), leaky gut syndrome, liver enzymes elevated, loss of memory, lymphadenopathy, lymphoma - B-cell non-Hodgkin’s, lymphoma - cryptic intestinal T-cell (refractory sprue), lymphoma – non-Hodgkin, macroamylasemia, macrocytosis (red blood cells larger than normal), macrolipasemia, magnesium - low, malabsorption, melanoma, memory loss, migraine, miscarriage, monoarthritis – recurrent, multiple sclerosis (MS) – a possible link, muscle pain and tenderness, muscle spasms and cramps, muscle wasting, muscle weakness, nail problems, nausea, nervousness, neuropathy – peripheral, neutropenia (low white blood cells), nightblindness, nosebleeds – unexplained, obesity, occult blood in stool, ocular myopathy, osteitis fibrosa, osteomalacia, osteomalacic myopathy, osteonecrosis, osteopenia, osteoporosis, pancreatic insufficiency (poor digestion), panic attacks, parathyroid carcinoma, penicilllin V impaired absorption, phosphorus – low, pityriasis rubra pilaris, plasma proteins low, Plummer-Vinson Syndrome, PMS, pneumococcal septicemia, pneumonia – recurrent, polyglandular syndrome, polymyositis, potassium - low, premenstrual syndrome, primary biliary cirrhosis, primary sclerosing cholangitis, progressive multifocal leukoencephalopathy, prolactinemia, prothrombin time prolonged, prothrombinemia, prurigo nodularis, psoriasis, psoriatic arthritis, puberty – delayed, purpura – idiopathic thrombocytopenic, rhabdomyolysis – hypokalemic, rheumatoid arthritis, rickets, sarcoidosis, Schizophrenic Spectrum Disorders, scleroderma, seborrhea, short stature, Sjögren’s syndrome, skin rash – itchy, small intestinal bacterial overgrowth, smell - loss of, sperm abnormalities, spina bifida, sprue – refractory (see: gluten), steatorrhea (pale, malodorous, floating, hard-to-flush stools), stomach ulcer, stroke – premature, sugar intolerance, swelling, Systemic Lupus Erythematosus (SLE), taste - loss of, tetany, thrombocytopenic purpura – idiopathic, thyroid disease - juvenile autoimmune, tongue – red and/or burning, tremors, tuberculosis - increased susceptibility to, Turner’s syndrome, urinary tract infections – recurrent, urticaria - chronic hives, uveitis, vaginitis, vasculitis, vasculitis of the CNS (Central Nervous System), vitiligo, volvulus (twisted intestines), vomiting, weight gain – unexplained, weight loss – unexplained, xerophthalmia (dry eyes), zinc – low
Nearly one in one hundred people have gluten intolerance (gluten enteropathy, sprue, celiac sprue). In only fifty percent of them does the disease show with gastro-intestinal symptoms - the rest has non-intestinal symptoms. Be aware that many of these symptoms can also have other causes - this list does not replace a doctor who sees you! • Abdominal pain • Acanthosis nigricans • Addison’s disease • Alcoholism • Alkaline phosphatase (bone) elevated • Allergic rhinitis • Alopecia areata (patchy hair loss) • Amenorrhea (absence of menstrual period) • Anemia • Anemia – iron deficiency • Anemia - refractory • Anemia - vitamin B12 deficiency • Anti-endomysium antibodies (EMA) • Anti-gliadin antibodies (AGA) • Anti-tissue-transglutaminase antibodies (tTG) • Antiphospholipid syndrome (frequent miscarriages and other problems) • Anxiety • Aortic vasculitis • Apathy • Aphthous ulcers (mouth sores) • Appetite – poor • Arthritis • Arthritis – enteropathic • Arthritis - juvenile idiopathic • Asthma • Ataxia • Ataxia, progressive myoclonic • Atherosclerosis • Attention Deficit Hyperactive Disorder (ADHD) • Autism, learning disorders • Autoimmune cholangitis • Autoimmune diseases • Autoimmune hepatitis • Autoimmune thyroid disease • Balding – premature • Bipolar disorder • Bitot’s spots (foamy patches on whites of eye) • Bleeding – unexplained • Blepharitis • Bloating • Blurred vision • Bone fracture • Bone pain • Brain atrophy • Brain fog • Bronchiectasis • Cachexia (general wasting) • Calcium – low • Cancer - small cell of the esophagus • Cancer (adenocarcinoma) of the small intestine • Cancer of the esophagus • Cancer of the pharynx • Candida infections – recurrent • Cardiomegaly • Casein intolerance (cow mill “allergy”) • Cataracts • Cerebral perfusion abnormalities • Cheilosis (cracked lips and corners of mouth) • Cholesterol - low • Chorea • Chronic bullous dermatosis • Chronic fatigue syndrome • Colitis • Common variable immunodeficiency • Complications during pregnancy, labor, delivery and post-partum period • Congenital anomalies • Constipation • Copper deficiency • Coronary artery disease • Cortical calcifying angiomatosis • Cow mill “allergy” • Cutaneous vasculitis • Cutis laxa • Cystic fibrosis • Dairy intolerance • Delusions • Dementia • Depression • Dermatitis herpetiformis • Dermatomyositis • Diabetes Type I • Diabetes Type II • Diarrhea • Disorientation • Down syndrome • Dry eyes • Duodenal ulcers • Dysmenorrhea (painful menstrual periods) • Dyspareunia (painful sexual intercourse) • Dysphagia (difficulty swallowing) • Early menopause • Easy bruising • Ecchymosis • Eczema • Edema • Enteropathy Associated T-cell Lymphoma (EATL) • Epilepsy • Erythema nodosum • Esophageal motor abnormalities • Eyes – dry • Eyes - bloodshot • Erythema elevatum diutinum • Failure to thrive • Fatigue • Fatty liver • Folic acid (folate) deficiency • Food allergies - blood-mediated and cell mediated • Food cravings • Gall bladder – impaired motility • Gas • Gastric emptying – delayed • Gastritis • GERD - Gastro-Esophageal Reflux Disease • Glucose abnormalities - too low or too high • Grave’s Disease • Growth retardation • Gums – bleeding and swollen • Hair loss • Hallucination • Headache • Heartburn • Heart disease • Hemochromatosis • Hemosiderosis - idiopathic pulmonary • Hepatic granulomatous disease • High blood pressure • Homocysteine elevated • Hyperactivity • Hyperkeratosis - follicular • Hyperparathyroidism • Hypertension • Hyperthyroidism • Hypocalciuria • Hypogonadism • Hypoparathyroidism • Hyposplenism (atrophy of spleen) • Hypothyroidism • Hypotonia • Ichthyosis - acquired • Pulmonary hemosiderosis - idiopathic • IgA deficiency • IgA nephropathy • Impotence • Inability to concentrate • Infertility (in both sexes) • Insomnia • Intrauterine growth retardation • Iron deficiency anemia in pregnancy - severe • Irritable bowel syndrome • Keratoconjunctivitis sicca • Keratomalacia • Kidney stones • Lactose intolerance • Lassitude • Late menarche (late start of menstrual periods) • Leaky gut syndrome • Liver enzymes elevated • Loss of memory • Lymphadenopathy • Lymphoma - B-cell non-Hodgkin’s • Lymphoma - cryptic intestinal T-cell (refractory sprue) • Lymphoma – non-Hodgkin • Macroamylasemia • Macrocytosis (red blood cells larger than normal) • Macrolipasemia • Magnesium low • Malabsorption • Melanoma • Memory loss • Migraine • Miscarriage • Monoarthritis – recurrent • Mouth sores • Multiple sclerosis (MS) – a possible link • Muscle pain and tenderness • Muscle spasms and cramps • Muscle wasting • Muscle weakness • Nail problems • Nausea • Nervousness • Neuropathy - peripheral • Neutropenia (low white blood cells) • Nightblindness • Nosebleeds – unexplained • Obesity • Occult blood in stool • Ocular myopathy • Osteitis fibrosa • Osteomalacia • Osteomalacic myopathy • Osteonecrosis • Osteopenia • Osteoporosis • Pancreatic insufficiency (poor digestion) • Panic attacks • Parathyroid carcinoma • Penicilllin V impaired absorption • Phosphorus - low • Pityriasis rubra pilaris • Plasma proteins low • Plummer-Vinson Syndrome • PMS (premenstrual syndrome) • Pneumococcal septicemia • Pneumonia – recurrent • Polyglandular syndrome • Polymyositis • Potassium - low • Primary biliary cirrhosis • Primary sclerosing cholangitis • Progressive multifocal leukoencephalopathy • Prolactinemia • Prothrombin Time prolonged • Prothrombinemia • Prurigo nodularis • Psoriasis • Psoriatic arthritis • Puberty - delayed • Purpura – idiopathic thrombocytopenic • Rhabdomyolysis - hypokalemic • Rheumatoid arthritis • Rickets • Sarcoidosis • Schizophrenic Spectrum Disorders • Scleroderma • Seborrhea • Short stature • Sjögren’s syndrome • Skin rash – itchy • Small intestinal bacterial overgrowth • Smell - loss of • Sperm abnormalities • Spina bifida • Sprue - refractory • Steatorrhea (pale, malodorous, floating, hard-to-flush stools) • Stomach ulcer • Stroke – premature • Sugar intolerance • Swelling • Systemic Lupus Erythematosus (SLE) • Taste - loss of • Tetany • Thrombocytopenic purpura – idiopathic • Thyroid disease - juvenile autoimmune • Tongue – red and/or burning • Tremors • Tuberculosis - increased susceptibility to • Turner’s syndrome • Urinary tract infections - recurrent • Urticaria - chronic hives • Uveitis • Vaginitis • Vasculitis • Vasculitis of the CNS (Central Nervous System) • Vitiligo • Volvulus (twisted intestines) • Vomiting • Weight gain – unexplained • Weight loss – unexplained • Xerophthalmia (dry eyes) • Zinc - low I will add to this list as I come across new links –keep checking! Read More 
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National Celiac Disease Awareness Day September 13th

September 21, 2010
Tags: food, agriculture, arthritis, autoimmune diseases, barley, Bread, celiac disease (see: gluten), cake, cancer, celiac sprue (see: gluten), civilization, cookies, Culture, dairy, depression, diabetes type II, earth, exploitation, fat, gluten, gluten intolerance, God, gods, inflammation, Iran, junk food, milk, monotheism, National Celiac Disease Awareness Day September 13th, nature, neurological problems, oats, pasta, Persepolis, polytheism, rye, skin diseases, sprue (see: gluten), vitamin B12 deficiency, wheat
National Celiac Disease Awareness Day September 13th Because we were traveling that day in Persepolis/Iran, I missed the date that reminded us of the most under-diagnosed disease there is: Gluten intolerance. Sprue, celiac sprue, celiac disease, gluten intolerance – they are all different names for the same disease – the one that turns your daily bread into poison. Inventing agriculture some five to ten thousand years ago was a huge step forward for mankind: Less people - especially children - starved, more survived – and more people had the leisure to turn to cultural endeavors (observing the stars, building cities, learning poetry). Agriculture is at the heart of our civilization. Of course, there was a price to pay: Some children could not tolerate the new foodstuffs on the table – milk and bread – and died. But most did very well. The population grew. Nature whispers to hunters and gatherers in the voice of the wind, the rustling of leaves, the babbling of brooks – everywhere spirits and gods seems to reside in holy nature places. Once farming has been invented, there’s really need only for a single God – the one who lets the wheat grow and fattens the cows so that they give milk: Give us our daily bread was the prayer ever since then. Leaving Nature behind and turning to monotheism also meant to exploit Earth and go for effectivity in all our endeavors: It made us great – and destroyed our old mother-ship Earth. Except that the gluten (the sticky protein in wheat that makes dough so doughy) can cause myriad diseases: diabetes, arthritis, cancer, depression, autoimmune disease, skin diseases, neurological problems, vitamin B12 deficiency, and so on, and so on. (I am working on a comprehensive list of gluten-related diseases – will come soon). And gluten is not only found in wheat – it also is in rye, barley and – as a slightly different but related protein – in oats. You know the story from the Bible about the Golden Calf? Well, in Persepolis I got an idea why the Golden Calf was such a threat Abraham’s God: It was a fall-back into the era of many gods, polytheism. Worse: it went directly to where the money was: to the cow. The One God had to be angry if they could circumvent him. Look at the picture of one of those double-cow capitals of Persepolis – on the “medical questions?” page here). But back to gluten: About one in a hundred (or a little less – depending on your ethnic background) cannot digest gluten well. If you are reddish or blond, blue-eyed and fair-skinned, you have higher likelihood to be intolerant to gluten – but I have certainly seen the disease in dark-haired people; even in Africans and Asians. There is not cure for celiac disease – the only recourse is to leave out all gluten in your diet. Some people have a hard time to let go of bread, cookies, cake and pasta. But once you realize that you can eat rice, beans, lentils, garbanzos as much as you want, you suddenly are not only disease-free but you certainly live healthier because all our junk food is based on wheat (and fat). You might have guessed it: If you are already depriving yourself of all fun in life, you can as well drop milk and dairy products – as they are the other big culprit at the root of many inflammatory processes in your body. Read More 
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