Resveratrol - a phyto-nutrient in red wine - is the wonder “drug” that is credited with the so-called French Paradox, namely that the French smoke more and eat more fat, and still have less heart disease, is explained by this. Even doctors now recommend a daily glass of wine.
I dunno. Perhaps their better health might have to do with that the French mostly eat fresh food, take two or three hours for their biggest meal of the day to share with family and friends, and have it more often at midday than in the evening. And they sleep more.
Not to take away from the wonderful goods resveratrol delivers in the body. Resveratrol is an anti-oxidant produced by the vine that gives us wine to fight off attacks by fungi and bacteria. In mice and rats, resveratrol has been shown to be anti-inflammatory, and prevent heart disease, diabetes and cancer. Allegedly, it also prolongs life (no real proof yet!).
It sounds like this is the stuff we should eat.
But should we eat it as a supplement? Probably not.
Every time we find a super drug,” a few years later it turns out that too much of a good thing can be a bad thing. Besides, resveratrol supplements are not made from the real thing – they are synthesized in a factory.
So, have a little red wine now and then – definitely not daily. Drink water for thirst. And eat dolmades - those Greek/Turkish vine leaves filled with rice and/or meat. What the wine advertisers don’t tell you: There is quite a bit more of resveratrol in vine leaves than in wine – and without the intoxicating effects. Unfortunately, there is even less in grapes and grape juice.
Interestingly, even if one takes high doses of resveratrol, only very little of cab be detected in the blood – your liver hurries to turn this “super drug” ineffective very quickly by changing its chemistry. To me this says: Don’t overdose on this drug! The body does not like it in high doses. As many phyto-nutrients, they should be taken often but in small doses, and that is best accomplished by eating a varied diet - like our ancestors the cave men did.
P.S. Occasionally, I get asked if "once in a while" it is okay to take a supplement. Because we don't always get around to eat healthili.
To which I answer: We should. - But apart from that: If one takes a supplement, it should probably be a low-dosed vitamin or anti-oxidant. Because taking high-dosed supplements adds to the toxic burden. Read More
Blog: On Health. On Writing. On Life. On Everything.
Autoimmune Diseases
July 11, 2010
In autoimmune diseases the body’s immune system turns against cells of the own body, slowing destroying them, creating havoc like thyroid problems, allergies, arthritis and muscle weakness, skin afflictions, diabetes type I, neuropathy, autism (at least some forms), fibromyalgia, kidney failure, multiple sclerosis, urticaria, psoriasis, chronic fatigue, bowel troubles – and many more.
Autoimmune diseases are on the rise – more people are suffering from them. Doctors are baffled and, on the whole, helpless. Strong medications like cortisone with myriad side-effects are employed, without getting to the root cause of autoimmune diseases.
Some researchers suspect that our modern diet plays a big role; others blame pollutants in the environment or the fact that we have much less intestinal parasites (compared with cave men) which makes the idle immune system turning against the self. Modern medical drugs (to name just one example - statins - that can cause an autoimmune muscle disease) might contribute.
Of course, I don’t have all the answers either – but these are some ideas that helped patients:
• Make sure you don’t have a gluten intolerance. Test are notoriously unreliable; a better idea is to leave out all gluten (wheat, rye, barley, oats) and see if you improve. Many people feel so much better already after a week off gluten. Others need up to a year.
• Autoimmune diseases hurt the body at different organs. They all have in common an inflammatory effect. To do away with SAD (Standard American Diet) should therefore be the most important step: No sugar, no sweeteners, no white starches, no dairy (which might be the main culprit here!), no bad fats (nothing fried and processed). Instead: vegetables, vegetables, vegetables – and herbs, legumes, a bit meat and fish (but no deli). If you are not willing to cook for yourself and take yourself out of the mainstream food insanity, my hope for your recovery is slim.
• Moderate exercise: For a minimum, go for a walk everyday. Exercise produces anti-inflammatory molecules in your body.
• Bright light: Get some light outdoors. Not to the point of burning (autoimmune patients often have photo-sensitivity and are prone to easy sunburns). But light is important. If you have dark skin, you need more light. – Vitamin D might be what is protecting. I usually don’t give supplements; going outdoors daily and eating cod liver (delicious!) once a month should do the trick.
• Herbs (don’t take them all at once; try one after the other and give it time to work):
---Resveratrol; a strong anti-oxidant. Remember, there is far more resveratrol in the green vine leaves than in red wine – and nearly none in white wine and grape juice.
---Astragalus has shown some benefit. Just know that allergies are frequent in patients with autoimmune diseases. So, if you show signs of intolerance (upset stomach, aching joints, rash, etc.), stop the herb.
---Turmeric (its main ingredient curcumin) has anti-inflammatory properties is.
---Green tea.
---Korean Gamgungtang.
---Padma28, a Tibetan formula. There are some controversies about this. Talk this through with a knowledgeable physician.
---Zyflamend, a blend of several anti-inflammatory herbs. Make sure you don't have an allergy to any of its components.
---Artemisia (vulgaris and annua) both have shown some anti-inflammatory effects.
---Olive leaf extract.
---Cordiceps, a medicinal mushroom. – Eating mushrooms generally has a good effect on the immune system. Just never eat them raw (they could cause cancer): Always cook mushrooms!
---Alfalfa sprouts.
---Gluscosamine, while not an herb in the strict sense, has shown anti-inflammatory promise.
---Bupleurum, a Chinese medicinal plant.
• Be careful with vaccinations. A link between shots and autoimmune disease is suspected by some researchers. That does not mean you should avoid all vaccinations; just stick to the essential ones. Discuss this with your physician – who hopefully has an open ear for alternatives. The link between vaccines and autoimmune disease might come from the suppressing of the normal function of the body, namely fighting viruses off; or might be a function of certain additives in vaccines like mercury, aluminum and squalene.
• Selenium might be missing in your diet (Brazil nuts have the highest amount of selenium, but most nuts have some; seafoods are more moderate sources of selenium). As you might have noticed, I am no friend of supplements: minerals (and vitamins) from a bottle are not the same, and have even been proven to be harmful by recent studies. – With nuts always stay aware that you might develop an allergy at any time.
• Add some good anti-inflammatory fish oil capsules (you should not belch up a fishy taste!) daily.
• Help your intestines with probiotics. The bowels might be at the root of autoimmune diseases: A chronically inflamed bowel (“Leaky Gut Syndrome”) leads to inflammation in other parts of your body.
• One study showed that calorie restriction might decrease inflammation. I would not aim for weight loss per se; eating a fresh diet might lead to weight loss anyway. But a one-day vegetable broth fast per week (see an earlier blog entry here) might be a good idea. – Interestingly, one study showed that fasting during infectious fevers reduced the risk of developing consequent autoimmune disease.
• Don’t try this at home … but nicotine seems to protect from autoimmune disease. So does cannabis (which is still illegal!).
If you want to know which of all the above ideas are most important – probably these: NO DAIRY, NO GLUTEN! Read More