Alexa Fleckenstein M.D.

Most arsenic poisoning is chronic: Through global trade, we are ingesting more and more arsenic-contaminated products – mainly rice, tea, medicinal herbs. Acute arsenic poisoning usually is accidental or occupational (mainly workers in pest control, electronics manufacturing industry and pressure-treated carpentry). Few are homi- or suicidal. Earlier this year I have been diagnosed with arsenic-induced ataxia. Ataxia means imbalance, wobbliness. For me, I am glad that I have “just” ataxia, and not more. The list below contains Latin as well a common names to make it easier to find things. Here is the short of what I have been doing to reduce my arsenic levels: 1. Stop using tainted products; look for safer sources. 2. Sauna as often as possible to sweat out heavy metals. Sweating through exercise and summer heat also helps. 3. Eating fresh garlic and cilantro bind and expel heavy metals 4. Vitamin C, selenium, vitamin B12, zinc, folate and methionine add to the elimination of arsenic. 5. And, of course, all the other lifestyle goodies: A healthy diet heavy on vegetables. Movement. Enough sleep. Plenty of water (some areas of the US have arsenic-contaminated drinking water from wells – careful!). Signs and Symptoms The myriad manifestations of arsenic intoxication do a roller coaster through all medical specialties, it seems. Since there are so many overlapping features with many diseases, it will take an open mind and special alertness to make a diagnosis. Just to show the enormous scope of signs and symptoms, I have thrown together acute and chronic arsenic intoxication. The list is not thought for diagnosing yourself - consult your physician. Here is the list: Abdominal discomfort Abdominal pain aches and pains Acrocyanosis Acute respiratory failure Acute tubular necrosis Adult respiratory distress syndrome Agitation Alopecia Altered mental status Anemia Anemia, aplastic Anhidrosis Anorexia Anxiety Aplastic anemia Arrhythmias Ascites Ataxia Atherosclerotic disease Autonomic neuropathy: unstable blood pressure, anhidrosis, sweating, flushing Basal cell carcinomas Basophilic stippling Birth defects, Blackfoot disease – black, mummified dry gangrene Bladder cancer Blood in the urine Bone marrow suppression Bowen disease Brittle Nails Bronchitis Bronchospams (inhaled arsenic) Burning in mouth/esophagus/stomach/bowel Cancer – lung, liver, kidney, bladder, skin, colon, larynx, lymphoid system Capillary dilation with fluid leakage and third spacing Cardiac arrhythmias Cardiac arrest Cardiomyopathy Carotid atherosclerosis Cerebral infarction Cerebrovascular diseases Chills Cholangitis Cholecystitis Chronic lower respiratory diseases Cirrhosis Clear skin lesions such as acne CNS depression Colitis Colon cancer Coma Concentration - poor Confabulation Confusion Congestive heart failure Conjunctivitis Convulsions Coordination difficulties Corneal necrosis Corneal ulcerations Cough with/without expectoration Cramps, cramping muscles Cyanosis of the fingers Death Dehydration Delirium Depression Dermatitis Dermatitis allergic-type Dermatitis, exfoliative Desquamation of skin Diabetes Diarrhea, often severe and/or bloody Disordered thinking Disorientation Disseminated intravascular coagulation Drowsiness Dyspnea (when inhaled) Dysphagia Eczema Edema – non-pitting of hand and feet EKG changes: ST changes, QT prolonged, Torsades de pointes, T wave inversion Encephalopathy, acute Enzyme inhibition Esophagitis Eyes blood-shot Eyes burning Facial edema Fatigue Fatty liver Fever - lowgrade Fibrillation, ventricular Fingernail pigmentation Fingernails with white marks Fluid loss Flushing Folic acid deficiency Gallbladder inflammation Gangrene of limbs Garlic-smelling breath or body fluids Gastritis Gastro-intestinal bleeding Generalized muscle aches and body pains Gingivitis Goiter Guillain-Barre syndrome - resembling Hair loss Hallucinations Headaches Hearing loss Heart disease Hematuria Hemoglobinuria Hemolysis Hepatomegaly Herpes Hormone imbalance Hyperesthesia Hyperpigmentation of the nails and skin Hyperpyrexia Hyperkeratosis thickening of the skin of the palms and soles Hypersalivation Hypertension Hypertension-related cardiovascular disease Hypopigmentation – “raindrop” areas of lost skin color Hypotension Hypovolemia Immune functioning impaired Immune suppression Impaired healing Inhibition of sulfhydryl enzymes – garlicky odor to breath/stool Insomnia Irritability Ischemic heart disease Jaundice Karyorrhexis Keratosis Kidney cancer Kidney damage Kidney failure Korsakoff’s psychosis Lack of appetite Landry-Guillain-Barré syndrome - resembling Larynx cancer Laryngitis Leg cramps Lens opacity Lethargy Leukemia??? Leukocyturia Leukonychia striata Leukopenia Lightheadedness Listlessness Liver cancer Liver: central necrosis Liver congestion Liver dysfunction and elevated liver enzymes Liver: fatty degeneration Low grade fever Lung cancer Lung: Chronic restrictive/obstructive diseases Lungs: Inflammation of respiratory mucosa Lung irritation Lymphoma??? Major depression – mimicking Malabsorption Malaise Mees's lines, or Aldrich-Mees's Melanosis of the eyelids, areolae of nipples, and neck Memory loss Memory – poor Mental retardation Mental status altered Metallic taste in mouth Microcirculation abnormalities Mitochondrial dysfunction Movement disturbances Muscle aches, spasms, weakness Muscle fasciculations Muscle tenderness Muscle twitching Muscle wasting Muttering Myocardial depression Myocarditis Nasal mucosa irritation (when inhaled) Nasal septum perforation Nausea Neuralgia Neuritis Night blindness Nightmares Numbness Oliguria Oral burns (acute, when taken by mouth) Pancreatitis Paralysis Paranoia Paresthesia – symmetrical, stocking-glove Pedal edema Pericarditis Peripheral neuritis Peripheral neuropathy Peripheral vascular insufficiency Personality change Pigmentation changes – hypo and hyper Pins and needles in hands and feet Pneumonia, bronchial Polyneuritis Portal fibrosis Proteinuria Psychosis Pulmonary edema Pulmonary insufficiency (emphysematous lesions) Pulse – irregular Quadriplegia Raynaud’s Syndrome Renal cortical necrosis Respiratory failure, acute Respiratory muscle insufficiency Respiratory tract infection Rhabdomyolysis Rhino-pharyngo-laryngitis Rouleaux formation of red blood cells Salivation excessive Seizures Sensorimotor peripheral axonal neuropathy Sensory changes Shock Singing Skin bronzed Skin cancer Skin lesions and rashes, including vesiculation Skin pallor Sore throat Splenomegaly Squamous cell carcinoma Stomach pain Stomatitis Stroke Stupor Suicidal Swallowing difficulty Sweating, excessive Sweet metallic taste Tachycardia Throat constriction Thirst Thrombocytopenia Tingling Tracheobronchitis Tremor Tubular necrosis, acute Unsteady gait Uremia Vasodilation Vasospasm Vertigo Visual hallucinations Vitamin A deficiency Vitiligo Vomiting Vomiting blood Weakness of distal muscles – hands and feet Weight loss