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Alexa Fleckenstein M.D.

Blog: On Health. On Writing. On Life. On Everything.

Gluten-Related Symptoms and Diseases

September 24, 2010
Tags: order, abdominal pain, acanthosis nigricans, Addison’s disease, ADHD, Alcoholism, alkaline phosphatase (bone) elevated, allergic rhinitis, alopecia areata (patchy hair loss), amenorrhea (absence of menstrual period), anemia, anemia – iron deficiency, anemia – refractory, anemia - vitamin B12 deficiency, anti-endomysium antibodies (EMA), anti-gliadin antibodies (AGA), anti-tissue-transglutaminase antibodies (tTG), antiphospholipid syndrome (frequent miscarriages and other problems), anxiety, aortic vasculitis, apathy, aphthous ulcers, appetite – poor, arthritis, arthritis – enteropathic, arthritis - juvenile idiopathic, asthma, ataxia, ataxia - progressive myoclonic, atherosclerosis, Attention Deficit Hyperactive Disorder (ADHD), Autism, learning disorders, autoimmune cholangitis, autoimmune diseases, autoimmune hepatitis, autoimmune thyroid disease, balding – premature, bipolar disorder, Bitot’s spots (foamy patches on whites of eye), bleeding – unexplained, blepharitis, bloating, blurred vision, bone fracture, bone pain, brain atrophy, brain fog, bronchiectasis, cachexia (general wasting), calcium – low, cancer - small cell of the esophagus, cancer (adenocarcinoma) of the small intestine, cancer of the esophagus, cancer of the pharynx, Candida infections – recurrent, cardiomegaly, casein intolerance, cataracts, cerebral perfusion abnormalities, cheilosis (cracked lips and corners of mouth), cholesterol – low, chorea, chronic bullous dermatosis, chronic fatigue syndrome, colitis, common variable immunodeficiency, complications during pregnancy – labor - delivery and post-partum period, congenital anomalies, constipation, copper deficiency, coronary artery disease, cortical calcifying angiomatosis, cow mill “allergy”, cutaneous vasculitis, cutis laxa, cystic fibrosis, dairy intolerance, delusions, Dementia, depression, dermatitis herpetiformis, dermatomyositis, diabetes type I, diabetes type II, diarrhea, disorientation, Down syndrome, dry eyes, duodenal ulcers, dysmenorrhea (painful menstrual periods), dyspareunia (painful sexual intercourse), dysphagia (difficulty swallowing), early menopause, easy bruising, ecchymosis, eczema, edema, Enteropathy Associated T-cell Lymphoma (EATL), epilepsy, erythema nodosum, esophageal motor abnormalities, eyes – dry, eyes – bloodshot, erythema elevatum diutinum, failure to thrive, fatigue, fatty liver, folic acid (folate) deficiency, food allergies - blood-mediated and cell mediated, food cravings, gall bladder – impaired motility, gas, gastric emptying – delayed, gastritis, GERD - Gastro-Esophageal Reflux Disease, glucose abnormalities - too low or too high, gluten, Gluten-Related Symptoms and Diseases, Grave’s Disease, growth retardation, gums – bleeding and swollen, hair loss, hallucination, headache, Heartburn, heart disease, hemochromatosis, hemosiderosis - idiopathic pulmonary, hepatic granulomatous disease, high blood pressure, homocysteine elevated, hyperactivity, hyperkeratosis – follicular, hyperparathyroidism, hypertension, hyperthyroidism, hypocalciuria, hypogonadism, hypoparathyroidism, hyposplenism (atrophy of spleen), Hypothyroidism, hypotonia, ichthyosis – acquired, pulmonary hemosiderosis – idiopathic, IgA deficiency, IgA nephropathy, impotence, inability to concentrate, infertility, insomnia, intrauterine growth retardation, iron deficiency anemia in pregnancy – severe, irritable bowel syndrome, keratoconjunctivitis sicca, keratomalacia, kidney stones, lactose intolerance, lassitude, late menarche (late start of menstrual periods), leaky gut syndrome, liver enzymes elevated, loss of memory, lymphadenopathy, lymphoma - B-cell non-Hodgkin’s, lymphoma - cryptic intestinal T-cell (refractory sprue), lymphoma – non-Hodgkin, macroamylasemia, macrocytosis (red blood cells larger than normal), macrolipasemia, magnesium - low, malabsorption, melanoma, memory loss, migraine, miscarriage, monoarthritis – recurrent, multiple sclerosis (MS) – a possible link, muscle pain and tenderness, muscle spasms and cramps, muscle wasting, muscle weakness, nail problems, nausea, nervousness, neuropathy – peripheral, neutropenia (low white blood cells), nightblindness, nosebleeds – unexplained, obesity, occult blood in stool, ocular myopathy, osteitis fibrosa, osteomalacia, osteomalacic myopathy, osteonecrosis, osteopenia, osteoporosis, pancreatic insufficiency (poor digestion), panic attacks, parathyroid carcinoma, penicilllin V impaired absorption, phosphorus – low, pityriasis rubra pilaris, plasma proteins low, Plummer-Vinson Syndrome, PMS, pneumococcal septicemia, pneumonia – recurrent, polyglandular syndrome, polymyositis, potassium - low, premenstrual syndrome, primary biliary cirrhosis, primary sclerosing cholangitis, progressive multifocal leukoencephalopathy, prolactinemia, prothrombin time prolonged, prothrombinemia, prurigo nodularis, psoriasis, psoriatic arthritis, puberty – delayed, purpura – idiopathic thrombocytopenic, rhabdomyolysis – hypokalemic, rheumatoid arthritis, rickets, sarcoidosis, Schizophrenic Spectrum Disorders, scleroderma, seborrhea, short stature, Sjögren’s syndrome, skin rash – itchy, small intestinal bacterial overgrowth, smell - loss of, sperm abnormalities, spina bifida, sprue – refractory (see: gluten), steatorrhea (pale, malodorous, floating, hard-to-flush stools), stomach ulcer, stroke – premature, sugar intolerance, swelling, Systemic Lupus Erythematosus (SLE), taste - loss of, tetany, thrombocytopenic purpura – idiopathic, thyroid disease - juvenile autoimmune, tongue – red and/or burning, tremors, tuberculosis - increased susceptibility to, Turner’s syndrome, urinary tract infections – recurrent, urticaria - chronic hives, uveitis, vaginitis, vasculitis, vasculitis of the CNS (Central Nervous System), vitiligo, volvulus (twisted intestines), vomiting, weight gain – unexplained, weight loss – unexplained, xerophthalmia (dry eyes), zinc – low
Nearly one in one hundred people have gluten intolerance (gluten enteropathy, sprue, celiac sprue). In only fifty percent of them does the disease show with gastro-intestinal symptoms - the rest has non-intestinal symptoms. Be aware that many of these symptoms can also have other causes - this list does not replace a doctor who sees you! • Abdominal pain • Acanthosis nigricans • Addison’s disease • Alcoholism • Alkaline phosphatase (bone) elevated • Allergic rhinitis • Alopecia areata (patchy hair loss) • Amenorrhea (absence of menstrual period) • Anemia • Anemia – iron deficiency • Anemia - refractory • Anemia - vitamin B12 deficiency • Anti-endomysium antibodies (EMA) • Anti-gliadin antibodies (AGA) • Anti-tissue-transglutaminase antibodies (tTG) • Antiphospholipid syndrome (frequent miscarriages and other problems) • Anxiety • Aortic vasculitis • Apathy • Aphthous ulcers (mouth sores) • Appetite – poor • Arthritis • Arthritis – enteropathic • Arthritis - juvenile idiopathic • Asthma • Ataxia • Ataxia, progressive myoclonic • Atherosclerosis • Attention Deficit Hyperactive Disorder (ADHD) • Autism, learning disorders • Autoimmune cholangitis • Autoimmune diseases • Autoimmune hepatitis • Autoimmune thyroid disease • Balding – premature • Bipolar disorder • Bitot’s spots (foamy patches on whites of eye) • Bleeding – unexplained • Blepharitis • Bloating • Blurred vision • Bone fracture • Bone pain • Brain atrophy • Brain fog • Bronchiectasis • Cachexia (general wasting) • Calcium – low • Cancer - small cell of the esophagus • Cancer (adenocarcinoma) of the small intestine • Cancer of the esophagus • Cancer of the pharynx • Candida infections – recurrent • Cardiomegaly • Casein intolerance (cow mill “allergy”) • Cataracts • Cerebral perfusion abnormalities • Cheilosis (cracked lips and corners of mouth) • Cholesterol - low • Chorea • Chronic bullous dermatosis • Chronic fatigue syndrome • Colitis • Common variable immunodeficiency • Complications during pregnancy, labor, delivery and post-partum period • Congenital anomalies • Constipation • Copper deficiency • Coronary artery disease • Cortical calcifying angiomatosis • Cow mill “allergy” • Cutaneous vasculitis • Cutis laxa • Cystic fibrosis • Dairy intolerance • Delusions • Dementia • Depression • Dermatitis herpetiformis • Dermatomyositis • Diabetes Type I • Diabetes Type II • Diarrhea • Disorientation • Down syndrome • Dry eyes • Duodenal ulcers • Dysmenorrhea (painful menstrual periods) • Dyspareunia (painful sexual intercourse) • Dysphagia (difficulty swallowing) • Early menopause • Easy bruising • Ecchymosis • Eczema • Edema • Enteropathy Associated T-cell Lymphoma (EATL) • Epilepsy • Erythema nodosum • Esophageal motor abnormalities • Eyes – dry • Eyes - bloodshot • Erythema elevatum diutinum • Failure to thrive • Fatigue • Fatty liver • Folic acid (folate) deficiency • Food allergies - blood-mediated and cell mediated • Food cravings • Gall bladder – impaired motility • Gas • Gastric emptying – delayed • Gastritis • GERD - Gastro-Esophageal Reflux Disease • Glucose abnormalities - too low or too high • Grave’s Disease • Growth retardation • Gums – bleeding and swollen • Hair loss • Hallucination • Headache • Heartburn • Heart disease • Hemochromatosis • Hemosiderosis - idiopathic pulmonary • Hepatic granulomatous disease • High blood pressure • Homocysteine elevated • Hyperactivity • Hyperkeratosis - follicular • Hyperparathyroidism • Hypertension • Hyperthyroidism • Hypocalciuria • Hypogonadism • Hypoparathyroidism • Hyposplenism (atrophy of spleen) • Hypothyroidism • Hypotonia • Ichthyosis - acquired • Pulmonary hemosiderosis - idiopathic • IgA deficiency • IgA nephropathy • Impotence • Inability to concentrate • Infertility (in both sexes) • Insomnia • Intrauterine growth retardation • Iron deficiency anemia in pregnancy - severe • Irritable bowel syndrome • Keratoconjunctivitis sicca • Keratomalacia • Kidney stones • Lactose intolerance • Lassitude • Late menarche (late start of menstrual periods) • Leaky gut syndrome • Liver enzymes elevated • Loss of memory • Lymphadenopathy • Lymphoma - B-cell non-Hodgkin’s • Lymphoma - cryptic intestinal T-cell (refractory sprue) • Lymphoma – non-Hodgkin • Macroamylasemia • Macrocytosis (red blood cells larger than normal) • Macrolipasemia • Magnesium low • Malabsorption • Melanoma • Memory loss • Migraine • Miscarriage • Monoarthritis – recurrent • Mouth sores • Multiple sclerosis (MS) – a possible link • Muscle pain and tenderness • Muscle spasms and cramps • Muscle wasting • Muscle weakness • Nail problems • Nausea • Nervousness • Neuropathy - peripheral • Neutropenia (low white blood cells) • Nightblindness • Nosebleeds – unexplained • Obesity • Occult blood in stool • Ocular myopathy • Osteitis fibrosa • Osteomalacia • Osteomalacic myopathy • Osteonecrosis • Osteopenia • Osteoporosis • Pancreatic insufficiency (poor digestion) • Panic attacks • Parathyroid carcinoma • Penicilllin V impaired absorption • Phosphorus - low • Pityriasis rubra pilaris • Plasma proteins low • Plummer-Vinson Syndrome • PMS (premenstrual syndrome) • Pneumococcal septicemia • Pneumonia – recurrent • Polyglandular syndrome • Polymyositis • Potassium - low • Primary biliary cirrhosis • Primary sclerosing cholangitis • Progressive multifocal leukoencephalopathy • Prolactinemia • Prothrombin Time prolonged • Prothrombinemia • Prurigo nodularis • Psoriasis • Psoriatic arthritis • Puberty - delayed • Purpura – idiopathic thrombocytopenic • Rhabdomyolysis - hypokalemic • Rheumatoid arthritis • Rickets • Sarcoidosis • Schizophrenic Spectrum Disorders • Scleroderma • Seborrhea • Short stature • Sjögren’s syndrome • Skin rash – itchy • Small intestinal bacterial overgrowth • Smell - loss of • Sperm abnormalities • Spina bifida • Sprue - refractory • Steatorrhea (pale, malodorous, floating, hard-to-flush stools) • Stomach ulcer • Stroke – premature • Sugar intolerance • Swelling • Systemic Lupus Erythematosus (SLE) • Taste - loss of • Tetany • Thrombocytopenic purpura – idiopathic • Thyroid disease - juvenile autoimmune • Tongue – red and/or burning • Tremors • Tuberculosis - increased susceptibility to • Turner’s syndrome • Urinary tract infections - recurrent • Urticaria - chronic hives • Uveitis • Vaginitis • Vasculitis • Vasculitis of the CNS (Central Nervous System) • Vitiligo • Volvulus (twisted intestines) • Vomiting • Weight gain – unexplained • Weight loss – unexplained • Xerophthalmia (dry eyes) • Zinc - low I will add to this list as I come across new links –keep checking! Read More 
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Truth in Wine

July 13, 2010
Tags: water, food, order, anti-aging, anti-inflammatory, anti-oxidant, bacteria, cancer, diabetes type II, dolmades, French Paradox, fungi, grapes, grape juice, heart disease, meals - shared, phyto-nutrients, resveratrol, sleep, supplement, Truth in Wine, vine, vitamins, wine
Resveratrol - a phyto-nutrient in red wine - is the wonder “drug” that is credited with the so-called French Paradox, namely that the French smoke more and eat more fat, and still have less heart disease, is explained by this. Even doctors now recommend a daily glass of wine. I dunno. Perhaps their better health might have to do with that the French mostly eat fresh food, take two or three hours for their biggest meal of the day to share with family and friends, and have it more often at midday than in the evening. And they sleep more. Not to take away from the wonderful goods resveratrol delivers in the body. Resveratrol is an anti-oxidant produced by the vine that gives us wine to fight off attacks by fungi and bacteria. In mice and rats, resveratrol has been shown to be anti-inflammatory, and prevent heart disease, diabetes and cancer. Allegedly, it also prolongs life (no real proof yet!). It sounds like this is the stuff we should eat. But should we eat it as a supplement? Probably not. Every time we find a super drug,” a few years later it turns out that too much of a good thing can be a bad thing. Besides, resveratrol supplements are not made from the real thing – they are synthesized in a factory. So, have a little red wine now and then – definitely not daily. Drink water for thirst. And eat dolmades - those Greek/Turkish vine leaves filled with rice and/or meat. What the wine advertisers don’t tell you: There is quite a bit more of resveratrol in vine leaves than in wine – and without the intoxicating effects. Unfortunately, there is even less in grapes and grape juice. Interestingly, even if one takes high doses of resveratrol, only very little of cab be detected in the blood – your liver hurries to turn this “super drug” ineffective very quickly by changing its chemistry. To me this says: Don’t overdose on this drug! The body does not like it in high doses. As many phyto-nutrients, they should be taken often but in small doses, and that is best accomplished by eating a varied diet - like our ancestors the cave men did. P.S. Occasionally, I get asked if "once in a while" it is okay to take a supplement. Because we don't always get around to eat healthili. To which I answer: We should. - But apart from that: If one takes a supplement, it should probably be a low-dosed vitamin or anti-oxidant. Because taking high-dosed supplements adds to the toxic burden. Read More 
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Dairy III: Raw Milk

June 7, 2010
Tags: food, adulteration, allergen, antibiotics, arthritis, asthma, autoimmune disease, bacteria, butter, cancer, casein, cream, dairy, Dairy III: Raw Milk, depression, diabetes type II, E. coli, food processing, gluten, hay fever, heart disease, homogenization, hormones, infants, inflammation, listeriosis, milk, milk - raw, sinusitis, milk - organic, milk - skim, milk - whole, mucus-producing, obesity, pasteurization, pesticides, pus, toddlers, tuberculosis, yogurt
Raw, organic milk might be the last chance the dairy industry still has. Milk is an unnatural, adulterated and inflammatory agent that should not be eaten. Consuming raw milk, without adulteration, might redeem milk and milk products at least a little – it’s last stand, so to speak. Let me say it again: Dairy is a highly inflammatory, hormonal, mucus-producing, allergenic food that adds to the burden of asthma, hay fever, chronic sinusitis - not to mention obesity, heart disease, diabetes, cancer, depression, arthritis, autoimmune disease. I certainly would not give raw milk to infants and toddlers. We are neither cows nor calves, and cow milk is an unnatural food for children and grown-ups. But the industry does not want us to talk about it. Dairy adds nothing to bone health - on the contrary. The simple truth is that calcium occurs abundantly in vegetables, fruit, nuts and whole grains - PLUS, plants contain the other minerals that are needed for strong bones like magnesium, manganese, iron, zinc, phosphorus, boron, copper, etc. and which are lacking in dairy. "Organic" milk is ultra-high pasteurized for longer shelf-life. That is lamentable. But at least organic does not contain bovine growth hormone, antibiotics and pesticides. Pasteurization and homogenization, on the other hand, change the milk molecules and make them less recognizable for the body – hence have higher inflammatory potential. So what is it about raw, organic milk that makes it - slightly - better? It is less processed. Which means it contains less antibiotics, pesticides and no added hormones. Therefore it is less inflammatory, less allergenic and probably causes less cancer. Since the cows are healthier, the milk contains less pus and fewer bacteria. On the other hand, without pasteurization, diseases can be transmitted through and extreme cleanliness and chilling are required for the whole process. With E. coli found repeatedly in lettuce and burgers, we know that we are susceptible to widespread epidemics from contaminated foods. Listeriosis is a real threat for pregnant women and their unborn children; the different strains of tuberculosis transmitted by cattle cannot be talked way. Still, I think that raw milk is probably not as dangerous as some people are telling us. I discourage the consumption of milk (see my earlier blogs). But if you insist - at least, have raw milk. So, if you have milk – which are the healthiest products? Top, in my opinion, are yogurts because they provide healthy bacteria for bowels – but the yogurt has to be plain, without sugar, fruit or any other additives – you might serve it with freshly cut fruit, of course. By definition, skim milk contains, relatively, more proteins and less fat, and since the proteins (eighty percent of which is the glue-like casein that is, chemically, related to gluten) are the inflammatory agent in milk, I would think that whole milk is better. Along that line of argument – and that might come as a surprise – cream and butter are the healthiest. In moderation, of course. Moderation is one of the problems: Casein breaks down in opioid-like substances, making all dairy addictive.  Read More 
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